STEAP Family Member 3, Metalloreductase (STEAP3) Peptide
STEAP3
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN984549
Quick Overview for STEAP Family Member 3, Metalloreductase (STEAP3) Peptide (ABIN984549)
Target
STEAP3
(STEAP Family Member 3, Metalloreductase (STEAP3))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-STEAP3 antibody (Catalog #: ARP43515_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- STEAP3 (STEAP Family Member 3, Metalloreductase (STEAP3))
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Background
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AS an endosomal ferrireductase, STEAP3 is required for efficient transferrin-dependent iron uptake in erythroid cells. It participates in erythroid iron homeostasis by reducing Fe(3+) to Fe(2+) and can also reduce of Cu(2+) to Cu(1+), suggesting that it participates in copper homeostasis. STEAP3 uses NAD(+) as acceptor (By similarity). It may play a role downstream of p53/TP53 to interface apoptosis and cell cycle progression. STEAP3 is indirectly involved in exosome secretion by facilitating the secretion of proteins such as TCT.
Alias Symbols: STMP3, TSAP6, dudlin-2
Protein Interaction Partner: BNIP3L,PKMYT1,TPT1,BNIP3L,PKMYT1
Protein Size: 498 -
Molecular Weight
- 56 kDa
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Gene ID
- 55240
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NCBI Accession
- NM_182915, NP_878919
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UniProt
- A8K6E3
Target
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